DIMITROV, Dimiter S.;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;CHEN, Weizao;THE UNITED STATES OF AMERICA; AS REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
DIMITROV, Dimiter S.,CHEN, Weizao
申请号：
USUS2011/037439
公开号：
WO2011/146891A3
申请日:
2011.05.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention provides engineered antibody domains (eAds), a polypeptide comprising a single domain CD4, as well as a fusion protein comprising the same. Nucleic acids encoding eAd and/or polypeptide or the fusion protein thereof, as well as compositions or cells comprising the eAd, polypeptide, fusion protein, or nucleic acid also are provided.L'invention concerne des domaines d'anticorps génétiquement modifiés (eAd), un polypeptide comportant un CD4 à domaine unique ainsi qu'une protéine hybride comportant celui-ci. L'invention concerne également des acides nucléiques codant pour eAd et/ou un polypeptide ou la protéine hybride de ceux-ci, ainsi que des compositions ou des cellules comportant l'eAd, le polypeptide, la protéine hybride ou l'acide nucléique.
