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COMPOSE AZABICYCLO ET SON SEL
专利权人:
TAIHO PHARMACEUTICAL CO.; LTD.
发明人:
KITADE, MAKOTO,OHKUBO, SHUICHI,YOSHIMURA, CHIHOKO,YAMASHITA, SATOSHI,OSHIUMI, HIROMI,UNO, TAKAO,KAWAI, YUICHI
申请号:
CA2767556
公开号:
CA2767556C
申请日:
2010.07.09
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
It is intended to provide a novel azabicyclo compound whichexhibits both HSP90 inhibitory activity and cell proliferationinhibitory effect. Specifically disclosed is a compoundrepresented by the following general formula (I) or a saltthereof: wherein X1 represents CH or N; any one of X2, X3 and X4represents N, and the others represent CH; any one or two of Y1,Y2, Y3 and Y4 represent C-R4, and the others are the same ordifferent and represent CH or N; R1 represents an optionallysubstituted monocyclic or bicyclic unsaturated heterocyclic grouphaving 1 to 4 heteroatoms selected from N, S and O; R2 representsan alkyl group having 1 to 6 carbon atoms, or the like; and R3 andR4 represent -CO-R5 or the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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