The present invention relates to a pharmaceutical combination. The pharmaceutical combination comprises a glucose kinase activator or a pharmaceutical salt of same, an isotope marker of same, a crystal form, hydrate, solvate, diastereomer or enantiomer form of same, and a PPAR receptor activator. The present invention further relates to a pharmaceutical composition, a fixed-dose compound preparation, and a preparation method for and uses of the pharmaceutical composition and of the fixed dose compound preparation.本發明涉及一種藥物組合，所述藥物組合包含葡萄糖激酶啟動劑或其可藥用鹽、其同位素標記物、其結晶形式、水合物、溶劑合物、非對映異構體或對映異構體形式和PPAR受體啟動劑。本發明進一步涉及藥物組合物、固定劑量複方製劑，以及所述藥物組合物和所述固定劑量複方製劑的製備方法及其用途。
