ALEXANDER, WILLIAM,XU, LIANG,HUANG, CHENG-CHENG,TANG, WENHUA,CHANG, ESTHER H.
申请号：
HK08100589.9
公开号：
HK1106952B
申请日:
2008.01.17
申请国别(地区):
HK
年份:
2012
代理人:
摘要：
Nucleic acid-immunoliposome compositions useful as therapeutic agents are disclosed. These compositions preferably comprise (i) cationic liposomes, (ii) a single chain antibody fragment which binds to a transferrin receptor, and (iii) a nucleic acid encoding a wild type p53. These compositions target cells which express transferrin receptors, e.g., cancer cells. These compositions can be used therapeutically to treat persons or animals who have cancer, e.g., head and neck cancer, breast cancer or prostate cancer.
