MEMORIAL SLOAN KETTERING CANCER CENTER;MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人:
CHEAL, SARAH M.,XU, HONG,LARSON, STEVEN M.,CHEUNG, NAI-KONG,WITTRUP, KARL DANE,TZENG, ALICE
申请号:
CA2976074
公开号:
CA2976074A1
申请日:
2016.02.09
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Described herein are multi-specific binding agents that bind A33 and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. Also provided herein are methods of using multi-specific binding agents or compositions thereof for the detection, prevention, and/or therapeutic treatment of diseases characterized by expression of the A33 glycoprotein antigen, in particular, colorectal cancer.