DÉRIVÉS DE 1-ARYLÉTHYL-4-ACYLAMINOPIPÉRIDINE SUBSTITUÉS À TITRE DE MODULATEURS DES RÉCEPTEURS D'OPIOÏDES/ADRÉNORÉCEPTEUR ALPHA ET LEUR PROCÉDÉ DE PRÉPARATION
The Arizona Board of Regents on behalf of the University of Arizona
发明人:
申请号：
EP15834369.9
公开号：
EP3183232A4
申请日:
2015.08.24
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The invention provides compounds that bind with high affinities to the μ-, δ- and κ-opioid receptors and α2-adrenoreceptor. In addition to providing these compounds with novel pharmacological binding properties, the invention also describes detailed novel methods for the preparation of representative compounds and a scheme for the synthesis of related compounds that bind to the opioid receptors and/or α2-adrenoreceptor.
