N- (methyl) -1H- pyrazol- 3 -amine, N- (methyl) -pyridin-2-amine and N- (methyl) -thiazol-2-amine derivatives for the treatment of diseases associated with amyloid or amyloid-like proteins, like e.g. Alzheimer's
Lopez Deber, Maria Pilar,Sreenivasachary, Nampally,Froestl, Wolfgang,Pihlgren Bosch, Maria,Muhs, Andreas,Lohmann, Sophie
申请号：
AU2007324696
公开号：
AU2007324696B2
申请日:
2007.11.23
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention relates to novel compounds of formula (II) that can be employedin the treatment of a group of disorders and abnormalities associated with amyloidprotein, such as Alzheimer's disease, and of diseases or conditions associatedwith amyloid- like proteins. The compounds of the present invention can alsobe used in the treatment of ocular diseases associated with pathological abnormalities/changesin the tissues of the visual system. The present invention further relates topharmaceutical compositions comprising these compounds and to the use of thesecompounds for the preparation of medicaments for treating, or preventing diseasesor conditions associated with amyloid and/or amyloid- like proteins. A methodof treating or preventing diseases or conditions associated with amyloid and/oramyloid- like proteins is also disclosed.
