BRACKLEY JAMES,BURGESS JOELLE LORRAINE,GRANT SETH,JOHNSON NEIL,KNIGHT STEVEN D.,LAFRANCE LOUIS,MILLER WILLIAM H.,NEWLANDER KENNETH,ROMERIL STUART,ROUSE MEAGAN B.,TIAN XINRONG,VERMA SHARAD KUMAR
申请号:
NZ60345411
公开号:
NZ603454A
申请日:
2011.05.05
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed are compounds of general formula (I), wherein the substituents are as defined herein. Further disclosed is a pharmaceutical composition comprising N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable excipient, for inhibiting the proliferation of and/or inducing apoptosis in cancer cells.