A COMPOSITION COMPRISING (-) -TRANS-3- (5, 6-DIHYDRO-4H-PYRROLO [3,2,1-IJ] QUINOLIN-1-YL)-4-(1H-INDOL-3-YL) PYRROLIDINE-2, 5-DIONE IN COMBINATION WITH A SECOND ANTI-PROLIFERATIVE AGENT
CHAN THOMAS C K,FRANCE DENNIS S,ISHII KENICHI,PUCCI PAOLO
申请号:
IN3233/KOLNP/2011
公开号:
IN2011KN03233A
申请日:
2011.08.01
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or a pyrroloquinolinyl-pyrrolidine-2,5-dione compound in combination with a therapeutically effective amount of a second anti-proliferative agent.