Compounds comprising 1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione system as inhibitors p53-Mdm2 protein-protein interaction

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专利权人:

Adamed Sp. z o.o.

发明人:

Feder, Marcin,Kalinowska, Iwona,Jaszczewska, Joanna Adriana,Burchard, Ewa,Lewandowski, Wojciech,Bulkowska, Urszula,Mazur, Maria,Wos, Katarzyna

申请号：

AU2015273106

公开号：

AU2015273106A1

申请日:

2015.06.11

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

A spirooxoindole compound represented by the formula selected from the group consisting of Formula (IA) and (IB), wherein all symbols are as defined in the description. The compound can find use in a method of prevention and/or treatment of diseases selected from the group consisting of cancer, immune diseases, inflammatory conditions, allergic skin diseases associated with excessive proliferation, and viral infections.

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