UAB Research Foundation;Lipimetix Development, LLC
发明人:
Anantharamaiah, G.M.,Goldberg, Dennis
申请号:
AU2014239186
公开号:
AU2014239186B2
申请日:
2014.03.14
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The disclosure provides dosing regimens and methods for treating atherosclerosis with an effective amount of Apo E mimetic to provide sustained therapeutic effects even after withdrawal of the treatment. The dosing regimens and methods involve a treatment cycle followed by a rest phase wherein a subject is administered an effective amount of an Apo E mimetic during the treatment cycle and no Apo E mimetic during the rest phase. The treatment cycle and the rest phase can vary.