Process for the Preparation of Rivaroxaban

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专利权人:

发明人:

Dharmaraj Ramachandra RAO,Geena MALHOTRA,Venkata Srinivas PULLELA,Manohar Raghunath SURVE,Hemant Sanjeevan DORLE,Kiran Balasaheb JADHAV

申请号：

US15506433

公开号：

US20170267669A1

申请日:

2015.08.24

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The present invention relates to an environmentally friendly process for preparing rivaroxaban. The present invention provides a process for preparing rivaroxaban of formula I, the process comprising: reacting a compound of formula VI with a base in the presence of a solvent to form a compound of formula VII and condensing the compound of formula VII with a compound of formula VIII or a compound of formula IX in the presence of a solvent to prepare rivaroxaban of formula I, wherein the solvent used in both steps comprises water.

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