QUART BARRY,ROSENBAUM DAVID,NEENAN THOMAS,BLANKS ROBERT
申请号:
NZ60934407
公开号:
NZ609344A
申请日:
2007.04.30
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed is the use of an inhibitor as defined herein, in the manufacture of a medicament for the treatment of diarrhoea-predominant Irritable Bowel Syndrome (d-IBS), wherein the inhibitor is selected from the group consisting of: - extract from Croton spp. or Calophyllum spp.; - latex from Croton spp. or Calophyllum spp.; - proanthocyanidin polymer composition from a Croton species or a Calophyllum species; and - crofelemer, wherein the amount of inhibitor is bioequivalent to crofelemer at a dosage of 50 mg per day to 750 mg per day.