The present invention relates to novel stable compressed vaccine composition comprising at least one anhydrous antigenic component comprising a stabilizer susceptible to foaming when the composition is mixed with liquid diluent; and an effective amount of a sugar alcohol.本發明係關於一種新穎穩定壓縮疫苗組合物,其包含至少一種無水抗原組分及有效量之糖醇,該無水抗原組分包含當該組合物與液體稀釋劑混合時容易發泡之穩定劑。