Dritte Patentportfolio Beteiligungsgesellschaft mbH & Co. KG
发明人:
Bernd Clement,Christiane Wolter-Reeh,Helen Schenk
申请号:
US14455272
公开号:
US09353047B2
申请日:
2014.08.08
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to a method for improving the bioavailability of pharmaceutical substances and for allowing the pharmaceutical substances to permeate the blood-brain barrier, the pharmaceutical substances having at least one or more amidine, guanidine, N-hydroxyamidine (amidoxime) or N-hydroxyguanidine functions. The invention also relates to medicaments containing the correspondingly modified pharmaceutical substances.