The present invention discloses a proximal humerus fixing device. The fixing device comprises: a fixer, a main nail, anti-rotation nails and locking nails; the fixer is disposed in a medullary cavity of the proximal humerus and is matched with the medullary cavity of the proximal humerus; the upper end of the fixer comprises a first contact portion and a second contact portion; the first contact portion is in contact with a head of the humerus and is of a plane structure; the second contact portion is in contact with the greater tuberosity of the humerus and is in a protrusion shape; the far end of the lower end of the fixer is in a bullet shape, and the lower end of the fixer is not in contact with the medullary cavity; the main nail is used for fixing the head of the humerus and the first contact portion; the head of each anti-rotation nail enters the head of the humerus, and the tail portion of each anti-rotation nail is fixedly connected with the fixer; the locking nails are disposed on the lower end of the fixer and are used for enabling the fixer and the humeral shaft to be fixedly connected with each other. The proximal humerus fixing device of the present invention is applied to the proximal humerus serious comminuted fracture complicated by or not complicated by shoulder dearticulation, the fixing treatment effect is good, and the surgical risk is small.