ROY, Shuvo,KANT, Rishi,POSSELT, Andrew,SONG, Shang,MOSES, Willieford,BLAHA, Charles
申请号:
EP17763924
公开号:
EP3426319A4
申请日:
2017.03.07
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
(57) Abstract: Bioartificial ultrafiltration devices comprising a scaffold comprising a population of cells enclosed in a matrix and disposed adjacent a plurality of channels are provided. The population of cells provides molecules such as therapeutic molecules to a subject in need thereof and is supported by the nutrients filtered in an ultrafiltrate from the blood of the subject. The plurality of channels in the scaffold facilitate the transportation of the ultrafiltrate and exchange of molecules between the ultrafiltrate and the population of cells.