PRODUÇÃO DE CORPOS DE OCLUSÃO DE VÍRUS QUE ENCERRAM VIRIÕES COMPREENDENDO GENOMAS DE DIFERENTES ESPÉCIES DE BACULOVÍRUS QUE PODEM SER UTILIZADOS PARA COMBATER PESTES DE INSETOS
ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODS ET PROCESSUS INDUSTRIELES (ARMINES);CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;UNIVERSIDAD PÚBLICA DE NAVARRA;INSTITUTO DE ECOLOGÍA,
发明人:
PRIMITIVO CABALLERO MURILLO,INÉS BEPERET ARIVE,OIHANE SIMÓN DE GOÑI,TREVOR WILLIAMS,MIGUEL LOPEZ-FERBER
申请号：
PT13766513
公开号：
PT3049516T
申请日:
2013.09.23
申请国别(地区):
PT
年份:
2018
代理人:
摘要：
Production of virus occlusion bodies that occlude virions comprising genomes of different species of baculoviruses that can be used to combat insect pests. A method is presented for the production of occlusion derived virions (ODVs) that simultaneously comprise genomes of different baculovirus species, occluded in a viral occlusion body (OB) with the structural and morphological features characteristic of baculoviruses. Mixed genome ODVs and OBs can be produced by co-infecting insect cells or insect hosts using two or more different baculoviruses species. Co-infection may be achieved by simultaneous inoculation of the different baculoviruses or with a time interval between inoculations, which results in different proportions of each species' genomes in the ODVs and OBs that are produced. The produced OBs can be used either directly for preparing an insecticide, or to infect susceptible insects to produce larger quantities of mixed genome ODVs and OBs, also useful for combating pest insects.
