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antibodies, bispecific antigen binding molecule, one or more isolated polynucleotides, one or more vectors, host cell, method for producing an antibody, pharmaceutical composition, uses, method for treating a disease in an individual and invention
专利权人:
F. HOFFMANN-LA ROCHE AG
发明人:
EKKEHARD MOESSNER,JENS NIEWOEHNER,LAURENT LARIVIERE,MAXIMILIANE KOENIG,THOMAS HOFER,TINA WEINZIERL
申请号:
BR112019018767
公开号:
BR112019018767A2
申请日:
2018.03.29
申请国别(地区):
BR
年份:
2020
代理人:
摘要:
the present invention relates generally to antibodies that bind to steap-1, including bispecific antigen binding molecules, for example, to activate t cells. moreover, the present invention relates to polynucleotides that encode these antibodies and vectors and host cells that comprise these polynucleotides. the invention further relates to methods for producing the antibodies and methods for using them in the treatment of diseases.a presente invenção refere-se, de modo geral, a anticorpos que se ligam a steap-1, incluindo moléculas de ligação a antígenos biespecíficas, por exemplo, para ativar células t. além disso, a presente invenção refere-se a polinucleotídeos que codificam esses anticorpos e vetores e células hospedeiras que compreendem esses polinucleotídeos. a invenção refere-se ainda a métodos para produzir os anticorpos e a métodos para usá-los no tratamento de doenças.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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