LEVER, Sarah,NARJES, Frank,OLSSON, Roine Ingemar,VON BERG, Stefan
申请号：
CL2018001573
公开号：
CL2018001573A1
申请日:
2018.06.13
申请国别(地区):
CL
年份:
2018
代理人:
摘要：
F AMP compound； OACUTE； RMULA(I)..R 1 stands for H (CO) R 4；R 2 is C1-6 tar.BicyclistCH2-CyclopropyleneO N5R 61. C1-6 is AMP； AACUTE；Alternative OH or Alcoxi C1-6 and C2-cyclopapile est amp； AACUTE；Choose halo insteadOhCN o alcoxi C1-6；R 3 is HC1-6Alcoxi C1-6,Halo or R 4 is: - H；- Replacement of C1-6 tar (R7)a；- Cyclopropyl propyl propyl-7 replaces the halo.C1-6OhCN,Alcoxi C1-6,1. C1-3-OR8 tenant；- Non-cyclododecane instead of C1-6U-OH tar；- Alcoxi C1-6；This is it!A is 1,2 or 3；R 6 is H1.C1-6 or cycloquilo C3-7 tar；278 R 7 was selected independently of the halo group.OhCN,Alcoxi C1-6,No. 9R 10Cyoquilo C3-7,HeterosexualThere, these cycling groups C3-7,Isopropyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl propyl2 or 3 selected groups independent of C1-6 asphalt group,CN,Oh2. Alcoxi C1-6 and NR11R 12；R 13 is H1.C1-6 or cycloquilo C3-7 tar；Each R5,R8,R9,R10,R11 and R12 are independent H or C1-6 asphalts.Or an acceptable drug salt and ampere salt.<；p>；UN COMPUESTO DE FÓ；RMULA (I), DONDE R 1 ES H O (CO)R4； R 2 ES ALQUILO C1-6, CICLOPROPILO, CH2-CICLOPROPILO, O NR5R 6, EN LA QUE DICHO ALQUILO C1-6 ESTÁ； OPCIONALMENTE SUSTITUIDO CON OH O ALCOXI C1-6 Y DICHO CH2-CICLOPROPILO ESTÁ； OPCIONALMENTE SUSTITUIDO CON HALO, OH, CN O ALCOXI C1-6； R 3 ES H, ALQUILO C1-6, ALCOXI C1-6, HALO O CN. R 4 ES: - H； - ALQUILO C1-6 OPCIONALMENTE SUSTITUIDO CON (R7)A； - CICLOALQUILO C3-7 OPCIONALMENTE SUSTITUIDO CON HALO, ALQUILO C1-6, OH, CN, ALCOXI C1-6, O ALQUILO C1-3-OR8； - HETEROCICLOALQUILO OPCIONALMENTE SUSTITUIDO CON ALQUILO C1-6 U OH； - ALCOXI C1-6； O - NHR13； A ES 1, 2 O 3； R 6 ES H
