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CONJUGATE VACCINE USING TRIMMING FUNCTION OF ERAP1
专利权人:
LTD.;SUMITOMO DAINIPPON PHARMA CO.
发明人:
Hitoshi BAN,Yukihiro NISHIO,Masashi GOTO,Yosuke TAKANASHI
申请号:
US14780241
公开号:
US20160045582A1
申请日:
2014.03.28
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides a compound represented by the formula (1):wherein Xa and Ya are each a single bond or the like, cancer antigen peptide A is an MHC class I-restricted cancer antigen peptide, andR1 is a hydrogen atom; a group represented by the formula (2):wherein Xb and Yb are each a single bond or the like, and cancer antigen peptide B is different from the cancer antigen peptide A and is an MHC class I or II-restricted cancer antigen peptide; a group represented by the formula (3):wherein Xc and Yc are each a single bond or the like, and cancer antigen peptide C is an MHC class II-restricted cancer antigen peptide; or cancer antigen peptide D, wherein the cancer antigen peptide D is an MHC class I or II-restricted cancer antigen peptide containing one cysteine residue,or a salt thereof, for example.
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