HUANG, RU CHIH,RULAND, CHRISTOPHER,LIANG, YU-CHUAN,CHUN, JONG HO,MOLD, DAVID
申请号:
EP13744007
公开号:
EP2809308A4
申请日:
2013.02.04
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention provides pharmaceutical compositions comprising derivatives of NDGA, including M4N (tetra-O-methyl nordihydroguaiaretic acid) and sorafenib and their use in the inhibition and treatment of neoplastic diseases, such as liver cancer, colon cancer, breast cancer, brain cancers and ovarian cancers, for example, in a subject. Compositions comprising derivatives of NDGA, including M4N, sorafenib and additional therapeutic agents are also provided.