The invention provides a biological dressing for treatment of a condition of the skin, mucosa, teeth or other tissue within or proximate to the oral cavity of a subject, the biological dressing comprised of a gum resin, a topically acceptable volatile solvent, and an oral care agent. The gum resin is present in a suitable amount that the composition, when the solvent evaporates, will dry to form a solid coating that sticks to the tissue to which the composition is applied and maintain the oral care agent over a sustained period of time in contact with sites on the tissue exhibiting symptoms of the condition. Methods are provided for treating symptoms of oral condition with such a oral care composition.