Compositions and methods for preventing or treating diseases, symptoms or processes characterized by abnormal fibroblast proliferation and extracellular matrix deposition
The present invention provides compositions and methods for preventing or treating a disease, condition or pathological process characterized by abnormal fibroblast proliferation and extracellular matrix deposition in a tissue of interest. The method comprises the step of administering a therapeutic amount of a pharmaceutical composition comprising a polypeptide having the amino acid sequence YARAAARQARAKALARQLGVAA (SEQ ID NO: 1) or a functional equivalent thereof and a pharmaceutically acceptable carrier.本発明は、対象の組織における異常な線維芽細胞の増殖及び細胞外マトリックスの沈着を特徴とする疾患、症状又は病理学的プロセスを予防又は治療する組成物及び方法を提供する。前記方法は、アミノ酸配列YARAAARQARAKALARQLGVAA（配列番号：1）を有するポリペプチド又はその機能的等価物及び医薬的に許容できる担体を含む医薬組成物の治療量を投与する工程を含む。
