Gary Allen Peltz;Hong-Hsing Liu;Guochun Liao;Timothy Alan Garrow
发明人:
Hong-Hsing Liu,Gary Allen Peltz,Guochun Liao,Timothy Alan Garrow
申请号:
US13395736
公开号:
US08685956B2
申请日:
2010.09.16
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present disclosure relates generally to a pharmaceutical compositions and methods of reducing acetaminophen-induced liver toxicity. The disclosure includes pharmaceutical compositions including acetaminophen and one or more components selected from S-adenosylhomocysteine (SAH), S-methylmethionine (SMM), or a pharmaceutically acceptable salt thereof. The disclosure also relates to methods of reducing acetaminophen-induced liver toxicity in a subject by administering or co-administering one or more of S-adenosylhomocysteine (SAH), S-methylmethionine (SMM), or a pharmaceutically acceptable salt thereof, with acetaminophen to a subject.