Purdue Research Foundation;CoMentis, Inc.;The Board of Trustees of the Unversity of Illinois;Oklahoma Medical Research Foundation
发明人:
Liu, Chunfeng,Ghosh, Arun K.,Ankala, Sudha,Lei, Hui,Bilcer, Geoffrey M.,Devasamudram, Thippeswamy,Kumaragurubaran, Nagaswamy,Swanson, Lisa M.,Tang, Jordan J.N.
申请号:
AU2006235344
公开号:
AU2006235344B2
申请日:
2006.04.10
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention provides novel beta-secretase inhibitors of the generalformula (I), where the variables A, A, L, L,L, R, R, R, R, R,R and R are as defined in the claims, a method for their usein treating Alzheimer's disease, and methods for their use in reducingmemapsin 2 catalytic activity.