A flossing device including a handle and a selectively lockable floss frame carrying a taught floss string is provided. The flossing device locks the floss frame to the handle to position the taught floss lengthwise parallel to the longitudinal axis associated with the handle. A locking assembly effectuates the selective locking engagement of the floss frame to the handle. The locking assembly may be positioned adjacent two arms formed in the handle defining a slot configured to slidably receive the floss frame.