BARBICK, JULIA E.,SHIRLEY, GARY B.,SARASAM, APARNA R.,GRABLE, CHARITY,BARNETT, ANGELA R.
申请号：
CA2872464
公开号：
CA2872464C
申请日:
2013.05.08
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
A medical device includes an implantable structure and a coating layer including a water-insoluble therapeutic agent and one or more additives selected from heparin, heparan sulfate, dextran and dextran sulfate, and physiologically- acceptable salts thereof. The one or more additives can be present in an amount effective to increase the rate of release of the water-insoluble therapeutic agent from the coating layer. The implantable medical device structure can be an expandable structure such as a balloon or stent. Also described are methods of making and using such implantable medical devices and coating layers.
