XIAO, HAI-YUN,DHAR, T. G. MURALI,LI, NING,DUAN, JINGWU,JIANG, BIN,LU, ZHONGHUI,NGU, KHEHYONG,PITTS, WILLIAM J.,TINO, JOSEPH
申请号：
CA2994717
公开号：
CA2994717A1
申请日:
2016.08.02
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Disclosed are compounds of Formula (I) or a salt thereof, wherein: A is CR1 or N； B is CR3 or N； D is CR4 or N； L1 is -(CR7R7)m-； L2 is -(CR7R7)n-； and X, Z, R1, R2, R3, R4, R5,and R6 are define herein. Also disclosed are methods of using such compounds as modulators of TNFa, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.
