A self-gripping hernia prosthesis (20) including a layer of repair fabric and a plurality of tissue grips (24) protruding from a surface of the repair fabric. The grip may be fabricated independent of the repair fabric and subsequently attached to the layer of fabric. A backing layer may be employed to secure each grip to the repair fabric. Each grip may include a base (30) that is located between the repair fabric (34) and the backing layer (36). Alternatively, the base may be attached directly to the backing layer. The tissue grips may be configured to minimize entanglement with the repair fabric.
