PRESERVING FUNCTIONALLY-COATED API PARTICLES PRODUCED BY SOLVENTLESS MIXING PROCESSES IN AQUEOUS SUSPENSION

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专利权人:

Catalent U.K. Swindon Zydis Limited

发明人:

Rosaleen MCLAUGHLIN,Adam PARKER,Jonathon WHITEHOUSE

申请号：

US16797934

公开号：

US20200268668A1

申请日:

2020.02.21

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Provided are pharmaceutical compositions and methods for preparing pharmaceutical compositions that preserve the coating of coated API particles in a pharmaceutical suspension. Pharmaceutical compositions include coated active pharmaceutical ingredient (API) particles comprising: an API particle； a first coating comprising one or more deformed components coating the API particle； a second coating comprising silica surrounding and/or partially or fully embedded into the first coating, a matrix former, and a structure former.

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