Phieng Siliphaivanh,Joey Methot,Kathryn Ann Lipford,Danielle Molinari,David L. Sloman,David Witter,Hua Zhou,Christopher Boyce,Xianhai Huang,Jongwon Lim,David Guerin,Ganesh Babu Karunakaran,Raman Kumar
申请号:
US15531759
公开号:
US09884048B2
申请日:
2015.12.10
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are ERK2 inhibitors. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and a pharmaceutically acceptable carrier. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and an effective amount of at least one other pharmaceutically active ingredient (such as, for example, a chemotherapeutic agent), and a pharmaceutically acceptable carrier.