Nucleic acids and the encoded CER2-like polypeptides, At1g68440-like polypeptides or DEAD-box RNA helicase polypeptides are provided. A method of enhancing yield-related traits in plants by modulating expression of nucleic acids encoding CER2-like polypeptides or At1g68440-like polypeptides is provided. A method of enhancing yield-related traits in plants by reducing or substantially eliminating expression of nucleic acids encoding DEAD-box RNA helicase polypeptides and/or the activity of DEAD-box RNA helicase polypeptides in said plants is provided. Plants with modulated expression of the nucleic acids encoding CER2-like polypeptides or At1g68440-like polypeptides have enhanced yield-related traits relative to control plants. Plants with reduction or elimination of the expression of endogenous nucleic acids encoding DEAD-box RNA helicase polypeptides have enhanced yield-related traits relative to control plants.
