Taipei Medical University;China Medical University
发明人:
Chieh-Hsi Wu,Yueh-Hsiung Kuo,Chun-Hsu Pan
申请号：
US14730430
公开号：
US20160355493A1
申请日:
2015.06.04
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention develops a series of methyl caffeate derivatives having biological activity in anti-angiogenesis. The present invention suggests that the compounds of the invention possess inhibiting angiogenesis through regulation of VEGF/VEGFR-2 and its downstream signaling cascades in the vascular endothelial cells (VECs).
