The present invention relates to a kind of preparation methods of Chinese materia medica preparation, it particularly relates to a kind of American Ginseng broken wall preparation. Invention is by being crushed into wall cell disruption powder for American Ginseng, pass through the control to ethanol solution and the quality of wall cell disruption powder, carry out alcohol-water wet granulation, and the extrusion forming under certain revolving speed, the universe is dry, this method granulating rate is high, thus obtained American Ginseng broken wall preparation bioavailability with higher, and preparation stability is strong, disintegration is good.本發明涉及一種中藥製劑的製備方法，具體來說，涉及一種西洋參破壁製劑。發明通過將西洋參粉碎成爲破壁粉，通過對乙醇溶液和破壁粉的質量的控制，進行乙醇‑水濕法制粒，並在一定的轉速下擠壓成型，乾燥，本方法成粒率高，由此製得的西洋參破壁製劑具有較高的生物利用率，並且製劑穩定性强、崩解性好。
