BANNER, DAVID,GUBA, WOLFGANG,HILPERT, HANS,MAUSER, HARALD,MAYWEG, ALEXANDER V.,NARQUIZIAN, ROBERT,PINARD, EMMANUEL,POWER, EOIN,ROGERS-EVANS, MARK,WOLTERING, THOMAS,WOSTL, WOLFGANG
申请号：
CA2776727
公开号：
CA2776727C
申请日:
2010.12.06
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention relates to 2-Amino-5,5-difluoro-5,6-dihydro-4H-[1,3]oxazin-4-yl)- phenyl]-amide derivatives of formula (I) having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.
