Compounds and methods for producing conjugated reagents

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专利权人:

シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッド

发明人:

ジュウ トゥオン,リーピン グオン,マーティン ドライナン

申请号：

JP2015507057

公开号：

JP6226958B2

申请日:

2013.04.11

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

Compositions are disclosed that include a support having on a surface thereof at least an inner polysaccharide layer and an outer polysaccharide layer. The outer polysaccharide layer has pendant moieties each comprising a terminal amine functionality. The point of linkage of the pendant moiety to the outer polysaccharide layer does not comprise an amide bond. The composition may be employed in a method of conjugating a member of a specific binding pair to a particle. The method comprises reacting the terminal amine functionality of the composition with the member of the specific binding pair, which comprises an amine-reactive functionality.

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