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Antibody against MCAM
专利权人:
PFIZER INC.
发明人:
ANDERSON, Karin
申请号:
PE2020000060
公开号:
PE20200616A1
申请日:
2018.07.13
申请国别(地区):
PE
年份:
2020
代理人:
摘要:
The antibodies referred to in this note include human antibodies and the parts of these antibodies that are specifically associated with MAdCAM, preferably MAdCAM's human body. The description refers to the human anti MAdCAM antibodies and the associated parts of these antibodies. Description refers to chemical antibodies, bisexual antibodies, secreted antibodies other than antibodies,A part of a single chain or fusion protein. Description refers to large and light chain immunoglobulins isolated from human anti MAdCAM antibodies and nucleic acid molecules encoded by this immunoglobulin. In addition, the method of producing human anti MAdCAM antibody is also mentioned in this note,Including these antibodies and methods for antibodies and components for diagnosis and treatment. The description provides a method for gene therapy using nucleic acid molecules to encode heavy and / or light immunoglobulin molecules, including human anti MAdCAM antibodies. Description refers to transgenic plants or animals including nucleic acid molecules in the description.La presente descripcion se refiere a anticuerpos que incluyen anticuerpos humanos y porciones de union al antigeno de estos que se unen especificamente a MAdCAM, preferentemente MAdCAM humana y que funcionan para inhibir MAdCAM. La descripcion se refiere ademas a anticuerpos anti-MAdCAM humanos y porciones de union al antigeno de estos. La descripcion se refiere ademas a anticuerpos que son anticuerpos quimericos, biespecificos, derivatizados, de cadena sencilla o porciones de proteinas de fusion. La descripcion se refiere ademas a inmunoglobulinas de cadenas pesadas y ligeras aisladas derivadas de anticuerpos anti-MAdCAM humanos y moleculas de acido nucleico que codifican tales inmunoglobulinas. La presente descripcion se refiere ademas a metodos para producir anticuerpos anti-MAdCAM humanos, composiciones que comprenden estos anticuerpos y metodos de uso de los anticuerpos y composiciones para el diagnostico y tratami
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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