International Business Machines Corporation;Agency for Science, Technology And Research
发明人:
申请号：
EP15849474.0
公开号：
EP3204441A4
申请日:
2015.09.01
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Water soluble biodegradable polymers were prepared by an organoacid catalyzed ring opening polymerization (ROP) of a cyclic carbonate monomer bearing an active ester side chain. The initial polymer comprising an active ester side chain was treated with an amino-alcohol, which transformed the active ester groups to N-substituted amide groups bearing mono-hydroxy alkyl groups and/or dihydroxy alkyl groups, thereby forming the water soluble polymers. The water-soluble polymers are non-toxic and exhibit stealth properties in buffered serum solution.
