Закрытое акционерное общество "Протеинсинтез" (RU)
发明人:
Макаров Олег Васильевич (RU),Волкова Елена Вячеславовна (RU),Копылова Юлия Владимировна (RU),Лысюк Елена Юрьевна (RU),Кибардин Алексей Владимирович (RU)
申请号:
RU2013114724/14
公开号:
RU2013114724A
申请日:
2013.04.02
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
A method of selecting tactics pregnancy with placental insufficiency (Mo) and syndrome fetal growth retardation (IUGR), comprising determining in the blood of pregnant with Mo and FGR angiogenic factors sFlt-1 - soluble fms-like tyrosine kinase and PIGF - placenta growth factor calculation angiogenic factor (Ka) according to the formula: Ka = sFlt-1 / PlGF × 10 and the choice of tactics further conduct pregnancy meaningfully angiogenic factor thus if Ka of less than or equal to 10 pregnant not need hospitalization is required dynamic observation, a doctor visit prenatal performed according to the plan in the event that more than 10 but less than 50 - pregnant woman is admitted to hospital carried cardiotocography (CTG), Doppler, determination of amniotic fluid index (AFI) carried out a treatment aimed at improving uteroplacental blood flow for 10 days: the volume infused is 400 ml per day, the drugs of choice are aktovegin, Trental, instenon, carnitine chloride 2 weeks exercise control ultrasound, Doppler, CTG, AFI, control angiogenic koefffitsienta in the absence of negative dynamics pregnant discharged in case Ka greater than or equal to 50 but less than 100 - pregnant woman is admitted to hospital, HIC is carried out, Doppler, AFI carried out a treatment aimed at improving uteroplacental blood flow for 14 days: the volume infused is 800 ml per day, the drugs of choice are aktovegin, Trental, instenon, carnitine chloride and control is performed Doppler CTG 1 every 3 days, 2 weeks - control Ka under floorСпособ выбора тактики ведения беременных с плацентарной недостаточностью (ПН) и синдромом задержки роста плода (СЗРП), включающий определение в крови беременной с ПН и СЗРП ангиогенных факторов sFlt-1 - растворимой fms-подобной тирозинкиназы и PIGF - плацентарного фактора роста, расчет ангиогенного коэффициента (Ka) по формуле: Ka=sFlt-1/PlGF×10 и выбор тактики дальнейшего ведения беременности по значению ангиогенного коэффициента при этом если Ka меньше или равен