The probe structure capable of measuring a pH level according to an embodiment of the present disclosure includes: a probe unit inserted into an experiment target a fixing body connected to a terminal of the probe unit and fixing the probe unit an electrode array disposed at a front end of the probe unit and sensing a neural signal from the experiment target and a pH level a reference electrode disposed at the front end of the probe unit to be spaced apart from the electrode array by a predetermined interval and sensing a reference signal for pH level measurement an electric wire electrically connected to the electrode array and the reference electrode and a measured signal collecting electrode integrated at the fixing body and collecting measured signals transmitted through the electric wire.