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NOUVELLE FORME CRISTALLINE D'ACIDE DIBUTANOÏQUE 4, 4'-[4-FLUORO-7-({4-[4-(3-FLUORO-2-MÉTHYLPHÉNYL) BUTOXY]PHÉNYL} ÉTHYNYLE)-2-MÉTHYLE-1H-INDOLE-1,3-DIYLE], D'ACIDE DIBUTANOÏQUE 4, 4'-[2-MÉTHYLE-7-({4-[4-(PENTAFLUOROPHÉNYL) BUTOXY]PHÉNYL} ÉTHYNYLE)-1H-INDOLE-1,3-DIYLE], ET D'ACIDE DIBUTANOÏQUE 4, 4'-[4-FLUORO-2-MÉTHYLE-7-({4-[4-(2, 3, 4, 6-TÉTRAFLUOROPHÉNYL) BUTOXY]PHÉNYL} ÉTHYNYLE)-1H-INDOLE-1,3-DIYLE]
专利权人:
LTD.;ONO PHARMACEUTICAL CO.
发明人:
TAKEUCHI, JUN,ITADANI, SATOSHI,UEDA, JUNYA,ONO, SHIZUKA,NEKADO, TAKAHIRO,FUJITA, MANABU
申请号：
EP11798106
公开号：
EP2583964A4
申请日:
2011.06.20
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
The present invention provides type C crystal of compound I, type B crystal of compound II, or type C crystal of compound III set forth in this specification.
来源网站：
中国工程科技知识中心
来源网址：
http://www.ckcest.cn/home/
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NOUVELLE FORME CRISTALLINE D'ACIDE DIBUTANOÏQUE 4, 4'-[4-FLUORO-7-({4-[4-(3-FLUORO-2-MÉTHYLPHÉNYL) BUTOXY]PHÉNYL} ÉTHYNYLE)-2-MÉTHYLE-1H-INDOLE-1,3-DIYLE]
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NOVEL CRYSTALLINE FORMS OF 4,4-[4-FLUORO-7-({4-[4-(3-FLUORO-2-METHYLPHENYL)BUTOXY]PHENYL}ETHYNYL)-2-METHYL-1H-INDOLE-1,3-DIYL]DIBUTANOIC ACID, 4,4-[2-METHYL-7-({4-[4-(PENTAFLUOROPHENYL)BUTOXY]PHENYL}ETHYNYL)-1H-INDOLE-1,3-DIYL]DIBUTANOIC ACID, AND 4,4-[4-FLUORO-2-METHYL-7-({4-[4-(2,3,4,6-TETRAFLUOROPHENYL)BUTOXY]PHENYL}ETHYNYL)-1H-INDOLE-1,3-DIYL]DIBUTANOIC ACID
Crystalline forms of 4, 4′-[4-fluoro-7-({4-[4-(3-fluoro-2-methylphenyl) butoxy] phenyl} ethynyl)-2-methyl-1H-indole-1,3-diyl] dibutanoic acid, 4,4′-[2-methyl-7-({4-[4-(pentafluorophenyl) butoxy] phenyl} ethynyl)-1H-indole-1, 3-diyl] dibutanoic acid, and 4,4′-[4-fluoro-2-methyl-7-({4-[4-(2, 3, 4, 6-tetrafluorophenyl) butoxy] phenyl} ethynyl)-1H-indole-1, 3-diyl] dibutanoic acid
NOVEL CRYSTALLINE FORMS OF 4,4'[4-FLUORO-7-({4-[4-(3-FLUORO-2-METHYLPHENYL)BUTOXY]PHENYL}ETHYNYL)-2-METHYL-1H-INDOLE-1,3-DIYL]DIBUTANOIC ACID,4,4'-[2-METHYL-7-({4-[4-(PENTAFLUOROPHENYL)BUTOXY]PHENYL}ETHYNYL)-1H-INDOLE-1,3-DIYL]DIBUTANOIC ACID,AND 4,4'-[4-FLUORO-2-METHYL-7-({4-[4-(2,3,4,6-TETRAFLUOROPHENYL)BUTOXY]PHENYL}ETHYNYL)-1H-INDOLE-1,3-DIYL]DIBUTANOIC ACID
