Martin BACHMANN,Andris ZELTINS,Paul PUMPENS,A‧澤爾汀斯,Paul PUMPENS,P‧普姆彭斯
申请号：
HK18114817
公开号：
HK1255670A1
申请日:
2018.11.20
申请国别(地区):
HK
年份:
2019
代理人:
摘要：
The present invention relates to virus-like particles of plant virus Cucumber Mosaic Virus (CMV), and in particular to modified VLPs of CMV comprising Th cell epitopes, in particular universal Th cell epitopes. Furthermore, these modified VLPs serve as, preferably, vaccine platform, for generating immune responses, in particular antibody responses, against antigens linked to said modified VLPs. The presence of the Th cell epitopes, in particular universal Th cell epitopes, led to a further increase in the generated immune response.
