Isooctyl or isoquinol derivatives and pharmaceutical components containing them for Bcl-2 anti Apocalypse inhibitors used in the treatment of cell, autoimmune diseases and immune system diseases
Brough, Paul,Chen, I-Jen,Davidson, James Edward Paul,De Nanteuil, Guillaume,Dodsworth, Mark,Fejes, Imre,Geneste, Olivier,Guillouzic, Anne-Françoise,Henlin, Jean-Michel,Kotschy, András,Le Diguarher, Th
申请号：
CU20160010
公开号：
CU24352B1
申请日:
2014.07.22
申请国别(地区):
CU
年份:
2018
代理人:
摘要：
<；p>； Isoindoline or isoquinoline derivatives of formula (I) useful as Bcl-2 antiapoptotic inhibitors <；/p>； <；p>； FORMULA SPACE <；/p>； <；p>； in which Het, R3, R4, R5, R7 , R8, R9, T, p, p ', q, and q' are as defined in the description and pharmaceutical compositions containing them. The compounds of the present invention have very valuable characteristics in the field of apoptosis and cancerology. <；/p>；<；p>；Derivados de isoindolina o de isoquinolina de fórmula (I) útiles como inhibidores antiapoptóticos Bcl-2<；/p>； <；p>；ESPACIO PARA FÓRMULA<；/p>； <；p>；en la que Het, R3, R4, R5, R7, R8, R9, T, p, p', q, y q' son como se han definido en la descripción y composiciones farmacéuticas que los contienen. Los compuestos de la presente invención tienen características muy valiosas en el campo de la apoptosis y la cancerología.<；/p>；
