1. Preparation and purification of (4S) - 4 - (4-cyano-2-methoxyphenyl) - 5-etoxi-2,8-dimethyl-1,4-dihydro-1,6-naftiridina-3-carboxamida and its purification as a drug activity principle
This is a procedure for preparing (4S) - 4 - (4-cyano-2-methoxyphenyl) - 5-etoxi-2,8-dimethyl-1,4-dihydro-1,6-nafturidina-3-preparation (I). This is a non stereoscopic antagonism of the ore receptor, which can be used for the prevention and / or treatment of cardiovascular and renal diseases such as heart failure and diabetes, nefroptia.Esta referido a un procedimiento para la preparacion de (4S)-4-(4-ciano-2-metoxifenilo)-5-etoxi-2,8-dimetilo-1,4-dihidro-1,6-naftiridina-3-carboxamida de formula (I). Este actua como antagonista no esteroideo del receptor mineralcorticoide y puede emplearse como preparado para la profilaxis y/o tratamiento de afecciones cardiovasculares y renales como insuficiencia cardiaca y nefropatia diabetica.
