DAI, YONG,GOLDBERG, ALAN, M,GOODE, MICHAEL, A,BARTOLUCCI, RAYMOND, ALAN,FRAZIER, JAMES, O
申请号:
NZ58013608
公开号:
NZ580136A
申请日:
2008.04.14
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a composition for tableting comprising an embedded lubrication matrix wherein the matrix consists of an oil finely dispersed in an oil insoluble material, and optionally a processing aide; wherein the embedded lubrication matrix is 0.3 percent to 8.8 percent of the composition; and wherein the composition is substantially free of stearate. Oils include Vitamin E, animal oil, synthetic oil, mineral oil, polyethylene glycol, silicon oil. Insoluble material includes: starch, dextrin, microcrystalline cellulose, ethylcelulose, gelatin, sugars, glucose, maltose, fructose, sorbitol, sucrose, mannitol, sorbitol, lactose, methylcellulose, hydroxypropylmethyl cellulose, maltodextrin, silicon dioxide, anhydrous dicalcium phosphate.