Androgen receptor modulating carboxamides

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专利权人:

Olli Törmäkangas

发明人:

Olli Törmäkangas,Gerd Wohlfahrt,Harri Salo,Rathna Durga Ramasubramanian,Pranab Kumar Patra,Arputharaj Ebenezer Martin,Terhi Heikkinen,Anniina Vesalainen,Anu Moilanen,Arja Karjalainen

申请号：

US14112727

公开号：

US08921378B2

申请日:

2012.04.20

申请国别(地区):

US

年份:

2014

代理人:

摘要：

Compounds of formula (I) or (II)wherein Rx, Rz, R9, R10, R14, R14′, R15, R15′, A and B are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds possess utility as tissue-selective androgen receptor modulators (SARM) and are useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.

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