Polypeptide containing DNA binding domain

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专利权人:

国立大学法人広島大学

发明人:

山本 卓,佐久間 哲史,落合 博,松浦 伸也,宮本 達雄

申请号：

JP2016086771

公开号：

JP6246258B2

申请日:

2016.04.25

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

PROBLEM TO BE SOLVED: To provide polypeptides which satisfy both of high functionality of the functional domain and high recognition specificity to DNA sequence, exert desired function with a high probability and safety, and are prepared by a simple method.SOLUTION: The invention provides: an artificial nuclease comprising a DNA binding domain and a functional domain linked with a polypeptide of 35-55 amino acids, where four DNA binding modules each of which has a different set of two amino acids at certain positions of the module are repeated forming a pattern in the DNA binding domain； a vector for expressing the artificial nuclease； a vector library for preparing the vector； and a vector set for preparing the vector library.SELECTED DRAWING: None

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/