TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
发明人:
MERALI, SALIM,BARRERO, CARLOS A.,CHILDERS, WAYNE E.,MORTON, GEORGE C.
申请号:
CA3093273
公开号:
CA3093273A1
申请日:
2019.03.07
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
In certain embodiments, this disclosure relates to methods of treating or preventing type 2 diabetes, pre-diabetes and conditions characterized by an increase in the levels of AIC, glucose, insulin, homeostasis model of assessment of insulin resistance (HOMA-IR), oxidative stress in adipose tissue, and earbonvlation of GLUT4 comprising administering an effective amount of a compound of Formula I-III as described herein, to a subject in need thereof.