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6-SUBSTITUTED 3-FLUORO-2-PYRIDINALDOXIME, 3-FLUORO-2-PYRIDINE HYDROXAMIC ACID, AND 3-FLUORO-2-PYRIDINAMIDOXIME SCAFFOLDS
专利权人:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人:
Rachid BAATI,Jagadeesh YERRI,José DIAS
申请号:
US16756240
公开号:
US20200255399A1
申请日:
2018.10.17
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed is a compound of formula (II), as well as to a process for preparing the compounds of formula (II) by a chemoselective Sonogashira reaction. It also relates to a pharmaceutical composition including at least one compound of formula (II) and at least one pharmaceutically acceptable support. Finally, it relates to the use of such a compound as a medicine, preferably in the treatment of a nervous and/or respiratory failure due to intoxication with at least one organophosphorous nerve agent; in the treatment of neurological diseases such as Alzheimer's disease; and/or in the treatment of cancer; and/or for use as antiviral drug.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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